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View Diary: Good News from Alzheimer's Researchers they may have found the magic bullet (164 comments)

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  •  One Bright Spot (10+ / 0-)

    in this news is that it's a drug that already exists and already has a track record as far as any side effects, so if it does prove effective there's a good chance it could be fast-tracked into use.

    •  it can be right now. (11+ / 0-)

      Off-list prescribing.

      If the drug is prescribable for condition X, physicians can prescribe it for other conditions if they choose and the patients are fully informed (or their caregivers).

      We will see "unofficial" clinical testing of this drug immediately, so results should be forthcoming faster than we might expect.

      "Minus two votes for the Democrat" equals "plus one vote for the Republican." Arithmetic doesn't care about your feelings.

      by G2geek on Thu Feb 09, 2012 at 07:08:36 PM PST

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      •  Would the application of it be different (1+ / 0-)
        Recommended by:
        G2geek

        than for its current use? I see somewhere further down that it's a topical for skin cancer. Would it have to be applied differently to affect the brain?

        Moderation in most things.

        by billmosby on Fri Feb 10, 2012 at 04:57:40 AM PST

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        •  "compounding pharmacists" are your friends. (3+ / 0-)
          Recommended by:
          billmosby, Just Bob, DamselleFly

          A compounding pharmacist is one who has the training to basically manufacture medications in his own lab.  

          So what s/he would do in this case, is buy the pure active ingredient, and instead of mixing it with a topical cream, mix it with whatever-it-takes to put it into capsules.  Or combine it with sterile saline into a liquid form that can be delivered to a doctor with hospital privs or a private clinic.  Then doc can have you come into the hospital or into the clinic, whereupon to give you a little needle with an IV line for delivery via that route.

          All of this is legal, though informed consent documents are a darn good idea, stating bluntly:  "Thou art making thyself into a guinea pig for the sake of the greater good; thou shalt not expect miracles when thou passeth through these doors."

          And if this stuff cleans out the nasties in your brain, splendid!  If it doesn't, well, nothing else was going to do the trick anyway.    

          "Minus two votes for the Democrat" equals "plus one vote for the Republican." Arithmetic doesn't care about your feelings.

          by G2geek on Fri Feb 10, 2012 at 05:55:35 AM PST

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          •  I was thinking of a couple of things. (2+ / 0-)
            Recommended by:
            G2geek, DamselleFly

            One would be that perhaps the active ingredient hasn't been tested well enough in brains to know if it would have some harmful effect that, while curing Alzheimer's, would leave you with Rush Limbaugh Syndrome or something.

            And another would be, we don't actually know if that particular brain nasty (beta amyloid) is a cause of, or an effect of, Alzheimer's.

            But this could help to provide the answer to that question and that would advance us one more step towards a cure.

            Moderation in most things.

            by billmosby on Fri Feb 10, 2012 at 06:58:07 AM PST

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            •  that's why the guinea pig consent form. (2+ / 0-)
              Recommended by:
              billmosby, DamselleFly

              If someone's got the big A, they're going to end up pooping in their diapers and drooling in their shoes and calling their closest relatives and friends by random names pulled out of the fog.  Sorry for being crass, but that's reality.  

              If I was faced with that kind of fate worse than death (thankfully it doesn't occur on either side of my family), I'd sign up to guinea pig my happy days away, on the faint hope that one or another of these magic molecules would go to work like an Elgin Pelican (look it up:-) and sweep up all the nasties in my crud-infested brain.

              Sooner or later someone's going to find one that works.  And then all the still-living guinea pigs can line up, open wide, gobble their pills with a nice drink of fresh orange juice, and then get back to being their fully lucid and mentally competent grouchy old selves until Saint Peter or some Bodhisattva comes a' calling for them.

              Yeeee-friggin'-hawww!

              "Minus two votes for the Democrat" equals "plus one vote for the Republican." Arithmetic doesn't care about your feelings.

              by G2geek on Fri Feb 10, 2012 at 08:17:25 AM PST

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