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View Diary: KosAbility: BREAKING: U.S. Senate Passes Gillibrand Amendment (153 comments)

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  •  Just be careful (4+ / 0-)

    too much ibuprofen is bad for kidney function

    "Why do we see the same old Republicans all over the news all the time when they were kicked out for screwing everything up?" - socratic's grandma

    by Michael James on Thu Nov 29, 2012 at 06:03:47 PM PST

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    •  I think he'd have to be taking it IV or swallowing (2+ / 0-)
      Recommended by:
      KelleyRN2, Cinnamon

      3 bottles a day, though.

      "I believe more women should carry guns. I believe armed women will make the world a better place. Women need to come to think of themselves not as victims but as dangerous." Anna Pigeon

      by glorificus on Thu Nov 29, 2012 at 08:08:23 PM PST

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      •  Actually (0+ / 0-)

        it doesn't take all that much, I think it's a question of long-term usage.

        If you are taking it day after day, it is a bad thing.  Certainly, higher doses would be worse, but high doses, even for fairly short durations have some significant effects depending on the person.

        It's an older study, but...

        Researchers at Johns Hopkins University in Baltimore, led by Dr. Andrew Whelton, gave participants above-normal doses of 800 milligrams of ibuprofen three times a day - the equivalent of 12 ibuprofen tablets - for up to 11 days.

        After eight days, three women developed kidney failure, which reversed when ibuprofen was discontinued. The remaining nine women, who received ibuprofen for 11 days, showed changes in kidney function but did not develop kidney failure.

        After recovering, the three women were given 400 milligrams of ibuprofen three times a day, equivalent to normal doses of the drug. Two of the three again developed kidney failure but recovered when the ibuprofen was stopped.

        (emphasis added by me)

        "Why do we see the same old Republicans all over the news all the time when they were kicked out for screwing everything up?" - socratic's grandma

        by Michael James on Fri Nov 30, 2012 at 11:38:40 AM PST

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        •  That's what I meant. They force-feed white rats (0+ / 0-)

          astronomically high doses, of course they get cancer or their kidneys shut down.

          Although specialized white rats bred for laboratory work may have there own genetic dispositions for cancer or renal failure.

          "I believe more women should carry guns. I believe armed women will make the world a better place. Women need to come to think of themselves not as victims but as dangerous." Anna Pigeon

          by glorificus on Fri Nov 30, 2012 at 02:44:50 PM PST

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          •  Best to avoid it if you can (0+ / 0-)

            I mean, pain is no fun, but I've completely stopped taking ibuprofen because I would rather just endure it than put my kidneys at risk.

            Also, not sure why you had the comment about white rats bred for lab work.  The link I posted was about a study of "12 women with mild kidney disease who also had arthritis and high blood pressure, two illnesses that often prompt its use."

            "Why do we see the same old Republicans all over the news all the time when they were kicked out for screwing everything up?" - socratic's grandma

            by Michael James on Fri Nov 30, 2012 at 03:38:29 PM PST

            [ Parent ]

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