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View Diary: Baby with HIV 'functionally cured' (46 comments)

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  •  We're living history folks. The bone marrow that (1+ / 0-)
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    cured the so-called Berlin patient has been tried in two other patients that I know of. The only reason they're not calling it a cure is because more research has to be done and those two are still on antivirals as a precaution. (If I remember correctly from the NPR story last fall.) With a new, non-invasive treatment for babies, I think we're looking at making this a treatable disease in the next 20 years. Exciting stuff.

    •  I agree, cautiously... (0+ / 0-)

      I think, and certainly hope, you are right. That having been said, I will withhold my optimism pending release of the primary literature of this case study, and, more importantly, the feasibility of replicating the results.

      I hope this is what it seems. I'm not sure, though.

      "Never argue with an idiot. They will drag you down to their level, and beat you with experience every time." --Unknown

      by Subwoofer of the House on Mon Mar 04, 2013 at 11:01:03 PM PST

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    •  Not quite. (0+ / 0-)

      The news about those other two cases is actually better than your comment suggests.  IIRC, the other two patients did not receive allogeneic bone marrow transplants from a donor with the CCR5-Delta 32 mutation.  They simply continued their ARV therapy during the transplantation process, and after they were done, researchers could not detect any HIV in their systems.  

      In that sense, their cases are actually more exciting than Timothy Brown's, because they didn't requiring locating compatible bone marrow donors who have that extremely rare mutation.

      Exciting stuff, indeed.

      "Ça c'est une chanson que j'aurais vraiment aimé ne pas avoir écrite." -- Barbara

      by FogCityJohn on Wed Mar 06, 2013 at 01:59:05 PM PST

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