From the AP:
Obama has picked Mona Sutphen and Jim Messina as his deputy chiefs of staff. Like Rouse, Messina has served as chief of staff for three different lawmakers — Sens. Max Baucus, D-Mont, Byron Dorgan, D-N.D., and Rep. Carolyn McCarthy, D-N.Y....
Sutphen is a foreign policy expert who has had several federal government positions, including as an aide to Bill Richardson when he was ambassador to the United Nations....
From the sound of it, Sutphen's focus would likely be foreign policy, while Messina's would be domestic. This presentation about the book she co-authored, "The Next American Century", is pretty impressive:
She's sitting on the right.
Couldn't find anything as detailed on Messina, but did find this interview:
Most important bipartisan accomplishment of your boss?
Senator Baucus was the chief reason bipartisan tax cut legislation was enacted in 2001.
Defining political event in your lifetime?
For me, Sen. Baucus 2002 re-election (I was the campaign manager). We had started the cycle with a scandal and finished with 63% of the vote, winning in a landslide.
Favorite aspect of your job?
Waking up every day realizing I can make my state and country a better place. I love that ability to get real things done.
Most important lesson learned?
The deal is always cut by the moderates in the middle, regardless of which party. And, your reputation is the most important form of political capital. Never do anything you wouldn't want on the front page of the newspaper.
Messina also served as chief of staff for Obama's presidential campaign.
There's another interview here too, but registration is required.
UPDATE: Better in-depth interview with Messina here:
Jim Messina took a Western path to becoming one of the nation's top Democratic operatives. Born in Denver 38 years ago, Messina went through Boise public schools and earned a University of Montana degree in political science. He began working in Montana campaigns, then branched out to campaigns in many other places. Often, his candidates have won, and he's worked his way up to be chief of staff for no less than three Democratic members of Congress. In June, he took leave from the headquarters of Montana Sen. Max Baucus, and moved to a borrowed apartment in Chicago to become chief of staff for Barack Obama's presidential campaign. Messina broke from his demanding, seven-days-a-week schedule to chat by phone with Ray Ring, High Country News senior editor, on a recent Saturday morning.