In an article in a recent AARP magazine, researchers for various US drug/pharmacy companies state that in that their experience, these companies typically inflate the research and development costs for new anti cancer drugs 10 times...This link is NOT to the original AARP article, but to one just released today...
http://www.truth-out.org/...
This article also points out how the pharmaceutical companies reap HUGE profits from the GOP's Medicare Part D law, that was written to maximize profits for the companies and keep costs high for the users. FWIW, The ACA/"Obamacare" was also written by republicans, the Heritage Foundation, to combat Hillary Clinton's single payer plan of the 1990's...and insurance companies are again reaping huge profits by being forced to do what they have been charging for-and not delivering-for decades.