Please also see TexMex's diary here
Below the jump are some ways to do that.
UNICEF
The World Food Program
The International Medical Corps
Mercy Corps
Doctors Without Borders
Googles Person Finder if you have information or are looking for someone.
Care
Oxfam America
American Jewish Joint Distribution Center
Samaritans Purse
AmeriCares
Direct Relief
Global Giving
Handicap International
Lutheran World Relief
Operation Blessing International
Operation USA
Plan International
World Vision
Real Medicine Foundation
Concern Worldwide
Catholic Relief Services
American Jewish World Service
Greater Good
Heifer International