With the BREXIT vote the people of Britain have made it clear that they do not approve of "Globalization" and it's negative impact on not just Britain but rest of the world as well, high unemployment, austerity, stagnant wages with a loss of "Sovereignty" in addition to a corrupt financial sector dictating economic policy giving rise to extremists in England and on the continent.
With recent developments the time has come for our President to scrap the trade agreements that are a detriment to our people, TPP, TTIP and TISA are DOA, any attempt to force them upon the American people could result in a "Worst case scenario" in which Donald Trump becomes our next President, Sec. Clinton and the Democratic party must do all that they can to prevent these agreements from being ratified, not just oppose them, stop them from ever being voted on.
With the BREXIT vote the door has been opened to the collapse of the E.U. , France, Sweden and the Czech Republic, the Netherlands and Denmark all have potential to vote on leaving the E.U. making TTIP moot, so ratification is pointless, the wise thing is to scrapp all these agreements and renegotiate them with "More transparency" and input from outside groups such as labor , consumer and environmental groups.