Something happens when the cells in a body "forget" that they are part of a larger organism, and no longer behave as though they depend on its continued survival to survive themselves. They begin behaving like single-celled organisms and consume resources around them as if it were the outside environment rather than part of the same biological infrastructure upon which they depend, becoming impervious to the regulatory signals of their surroundings until they kill both the host body and themselves. In other words, a constituent thrives because they're surrounded by cooperative multitudes, only to decide that they owe nothing back and may do whatever they please with the bounty they inherit regardless of the wider consequences - what does that sound like? The anti-government, anti-tax, anti-social strain of conservative ideology is quite simply cancer on a larger scale, and it has already eaten away at the economic and social foundations of many American states.
Though they depend on roads, highways, bridges, and tunnels to get anywhere, conservatives don't think they're obligated to contribute to their construction and maintenance. Though they benefit economically from both their own education and that of their employers, employees, or coworkers, conservatives don't think they owe anything to maintain and expand education. Though police and fire services protect their property, persons, and the communities that make their lifestyles possible, they don't consider it their obligation to contribute to these services. The same is true of pretty much every single public good that underlies their prosperity, from healthcare to public safety.
Quite simply, conservatives no longer recognize the existence of a society wider than themselves and their immediate circle of relationships and interests: They see everybody and everything around them either as prey or as an obstacle, as if the man-made environment that has coddled them their entire lives is a jungle and their passive inheritance of the work of others was an act of god-like creativity on their own part. As they devour the underpinnings of the society that created them, the infrastructure of civilization that made modern life possible begins to dissolve, reverting economic, social, and political relationships back to earlier and earlier forms. Free exchange of goods and services degenerates into manorialism, with individuals, dynasties, corporations, and identity groups de facto seceding from the United States to feed off its productivity without giving anything back.
"Give a man a fish, and he is fed for a day. Teach a man to fish, and he is fed for a lifetime." This was once a commonplace saying among conservatives, although they never really believed it - they've always preferred to keep education the domain of elites, and only teach the "unwashed masses" how to be obedient employees. But conservatives today would more likely add a third statement: "Enslave a fisherman, and you are fed for a lifetime without having to learn anything." There is always more surplus labor to exploit, and always more tissues for a malignant tumor to encroach upon. Until there isn't, but that's always generations after the road to ruin is begun - and the needs of future generations would be considered "tyrannical" to an egoist sociopath who sees everything outside themselves as prey.
The conservative cancer has already eroded many parts of previously livable American states into third-world shitholes, tearing out the easily-exploitable natural resources while leaving behind toxic wastelands, eviscerating education, allowing infrastructure to collapse, and leaving behind communities populated by ignorant, poor, tribalistic savages whose only refuge is religion and crystal meth. But even then they're exploited infinitely, because conservatives will sell both to them (after all, drug dealing is business, and conservatives love business), and then sell prisons to the state to incarcerate, brutalize, and dehumanize them further. But since people languishing in cells aren't productive, then they turn jails into slave quarters and use prisoners as sources of cheap, forced labor. Every step of the way, a little bit more of civilization disappears; a little more entropy cost is paid in the transition to the New Low as the conservative cancer searches for the ever-elusive absolute bottom. Society becomes ill, less able to defend itself against their onslaughts and predations, and their invasion only accelerates.
And then the body dies, along with all its healthy cells and cancer cells alike. There are no conservatives in a failed civilization, just as there are no shadows in absolute darkness - there is nothing against which to compare the pathologies they represent. Everyone is ignorant; everyone is focused on immediate, parochial needs at all costs because they have no choice, not because they're sociopaths like the cancervatives who put them in that position; and there is simply nothing that can be done, because they've reduced human existence to a state of base entropy where the slightest move to improve conditions is immediately torn apart by a million hopeless, degenerate animals struggling to survive one more instant. Conservatives are simply the death of civilizations.
But that doesn't mean there is no hope: Just as with literal cancer, we can imagine a "political oncology" that focuses on strategies for building up a healthy social immune system against cancervatism, and that articulates specific policies and both grassroots and authoritative activities that can limit its toxicity on the body politic. And we already have a legal surgical method for removing malignancies: It's called the RICO Act, and authorities need to work up the courage to begin using it to unravel the vast criminal networks of politically-connected conservatives. Here's hoping for an America in Remission.